Cystatin C Antibody

Description

Cystatin C Antibody

The Cystatin C Antibody is a high-specificity immunoreagent designed for the detection of human Cystatin C, a cysteine protease inhibitor widely recognized as a biomarker for renal function, cardiovascular risk, and neurological conditions. Affinity purified for optimal performance, this antibody targets Cystatin C isolated from human sources and is supplied in liquid form with 0.05% sodium azide preservative.

Validated for use in ELISA, Western blotting, and other immunoassay formats, it supports research in nephrology, oncology, and neurovascular studies. Its consistent reactivity and minimal cross-reactivity make it a reliable tool for both exploratory and clinical investigations. Researchers studying glomerular filtration rate, preeclampsia, or vascular cognitive impairment will find this antibody especially valuable.

Key benefits:

• Specific to human Cystatin C with minimal background

• Affinity purified for high purity and reproducibility

• Supplied in liquid format for immediate use

• Compatible with ELISA, WB, and other immunoassays

• Supports research in renal, cardiovascular, and neurological biomarkers

Products are for in vitro research use only (RUO).

References

• Cystatin C as a biomarker for estimating glomerular filtration rate. Ferguson TW, Komenda P, Tangri N. Curr Opin Nephrol Hypertens. 2015 May;24(3):295-300.
• Accuracy of cystatin C in prediction of acute kidney injury in children; serum or urine levels: which one works better? A systematic review and meta-analysis. Nakhjavan-Shahraki B, Yousefifard M, Ataei N, Baikpour M, Ataei F, Bazargani B, Abbasi A, Ghelichkhani P, Javidilarijani F, Hosseini M. BMC Nephrol. 2017 Apr 3;18(1):120.
• Serum cystatin c as predictive factor of preeclampsia: A meta-analysis of 27 observational studies. Bellos I, Fitrou G, Daskalakis G, Papantoniou N, Pergialiotis V. Pregnancy Hypertens. 2019 Apr;16:97-104.
• Cystatin C and cardiovascular or all-cause mortality risk in the general population: A meta-analysis. Luo J, Wang LP, Hu HF, Zhang L, Li YL, Ai LM, Mu HY, Kun-Wang. Clin Chim Acta. 2015 Oct 23;450:39-45.
• Corticosteroids significantly increase cystatin C levels in the plasma by promoting cystatin C production in rats. Zhu XR, Ge N, Wang Y, Zhai JL, Liu C. Ren Fail. 2019 Nov;41(1):698-703.
• Correlations of serum cystatinC level and gene polymorphism with vascular cognitive impairment after acute cerebral infarction. Zeng Q, Huang Z, Wei L, Fang J, Lin K. Neurol Sci. 2019 May;40(5):1049-1054.
• Accuracy of cystatin C for the detection of abnormal renal function in children undergoing chemotherapy for malignancy: a systematic review using individual patient data. Whiting P, Birnie K, Sterne JAC, Jameson C, Skinner R, Phillips B; Cystatin C in Childhood Cancer Collaboration Group. Support Care Cancer . 2018 May;26(5):1635-1644.